Abstract: Objective To determine the coverage of influenza vaccination and its main influencing factors among healthcare workers.Methods We conducted a cross-sectional survey in 1 217 healthcare workers from 30 medical institutions selected with two-stage random sampling.We obtained general information,knowledge about influenza and influenza vaccine,influenza vaccination during the winter season of 2010-2012,and acceptance of influenza vaccination among the healthcare workers,with face-to-face interview.Results Totally 172 healthcare workers were vaccinated during the influenza season of 2010-2012 in the healthcare workers,with a coverage rate of 12.37%.Among the healthcare workers,38.39% reported that they would accept influenza vaccination before the influenza season of 2012 and 62.13%reported that they would accepted influenza vaccination free of charge.The main reasons for the healthcare workers not accepting vaccination were limited efficacy of the vaccine(66.76%),side effects of the vaccine(55.52%),unnecessary vaccination for healthy person(54.15%),inconvenience of annual vaccination(43.20%),and the charge of vaccination(35.30%).Logistic regression analyses showed that knowing effectiveness of influenza vaccine,healthcare workers being the population recommended to be vaccinated,and knowing that the vaccination could be paid by health insurance were significantly associated with higher acceptance of influenza vaccine in the healthcare workers.While knowing that the influenza caccination should be administered annually decreased the perception of influenza vaccination in the healthcare workers.ConclusionThe influenza vaccination coverage and willingness to accept the vaccination were very low among healthcare workers in Ningbo city and lack of confidence to vaccine efficacy and safety,deficiency in awareness of influenza hazard,and the charge of influenza vaccine are main reasons for the healthcare workers without influenza vaccination.