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翁根龙, 徐怡芬, 陆建林. 社区老年人群颈动脉粥样硬化危险因素调查[J]. 中国公共卫生, 2018, 34(10): 1331-1333. DOI: 10.11847/zgggws1118148
引用本文: 翁根龙, 徐怡芬, 陆建林. 社区老年人群颈动脉粥样硬化危险因素调查[J]. 中国公共卫生, 2018, 34(10): 1331-1333. DOI: 10.11847/zgggws1118148
Gen-long WENG, Yi-fen XU, Jian-lin LU. Risk factors of carotid atherosclerosis among community elderly in Suzhou city: a cross-sectional study[J]. Chinese Journal of Public Health, 2018, 34(10): 1331-1333. DOI: 10.11847/zgggws1118148
Citation: Gen-long WENG, Yi-fen XU, Jian-lin LU. Risk factors of carotid atherosclerosis among community elderly in Suzhou city: a cross-sectional study[J]. Chinese Journal of Public Health, 2018, 34(10): 1331-1333. DOI: 10.11847/zgggws1118148

社区老年人群颈动脉粥样硬化危险因素调查

Risk factors of carotid atherosclerosis among community elderly in Suzhou city: a cross-sectional study

  • 摘要:
      目的  了解社区老年人群颈动脉粥样硬化(CAS)形成的相关危险因素,为相关疾病预防提供依据。
      方法  以江苏省苏州市汾湖高新区芦墟区域入选的60~80岁3 126名常住居民为研究对象。进行问卷调查、体格检查、血生化指标检查和双侧颈动脉彩色超声检查。
      结果  CAS形成1 183例,总患病率为37.84 %。年龄与患病率呈正相关;CAS患者有高血压、糖尿病、高脂血症、肥胖、吸烟、过量饮酒、缺乏运动比例更高(P < 0.001);与正常人群比较,CAS检出者空腹血糖、糖化血红蛋白(HbAlc)、总胆固醇、甘油三酯、低密度脂蛋白胆固醇(LDL-C)、血尿酸和血超敏C反应蛋白(Hs-CRP)水平升高,高密度脂蛋白胆固醇(HDL-C)水平降低,差异有统计学意义(P < 0.01);正常人群与CAS检出者在性别、适量饮酒方面差异无统计学意义(P > 0.05)。
      结论  社区老年人群CAS患病率随着年龄增长而增加,吸烟、肥胖、高血压、糖尿病、高血脂和高尿酸是CAS患病危险因素;有效控制血压等CAS危险因素,延缓CAS病变,可进一步减少心脑血管病的发生。

     

    Abstract:
      Objective  To explore risk factors of carotid atherosclerosis (CAS) in community elderly for providing evidences to interventions on CAS.
      Methods  A questionnaire survey, physical examination, biochemical detection, and bilateral carotid artery colour doppler ultrasonography were conducted among 3 126 permanent residents aged 60 to 80 years recruited in Luxu region of Fenhu High-Tech District, Suzhou Municipality from September 2013 to July 2014.
      Results  Among the participants, 1 183 CAS cases were identified; the CAS prevalence rate was 37.84% and positively correlated with age. The prevalence rates of hypertension, diabetes, hyperlipidaemia, obesity, smoking, excessive alcohol drinking, and lack of physical activity were all significantly higher among the CAS cases than among the participants without CAS (P < 0.001 for all). Among the CAS cases, the detection rates of elevated fasting blood glucose, glycosylated hemoglobin A1c (HbAlc), total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C), uric acid, and high-sensitivity C-reactive protein (Hs-CRP) were significantly higher and the level of low-density lipoprotein cholesterol (HDL-C) was significanlty lower than among the participants without CAS (all P < 0.001). No significant differences were observed in gender and moderate alcohol drinking between the participants with and without CAS (both P > 0.05).
      Conclusion  Prevalence of CAS increases with age and is correlated with factors such as smoking, obesity, high blood pressure, diabetes, high cholesterol, and high uric acid among community elderly in Suzhou city, suggesting that effective interventions on the risk factors should be carried out for the prevention of cardiovascular diseases in the population.

     

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