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PM2.5对慢性阻塞性肺疾病发生发展影响及药物治疗研究进展

孟灿 孙成昊 商磊

孟灿, 孙成昊, 商磊. PM2.5对慢性阻塞性肺疾病发生发展影响及药物治疗研究进展[J]. 中国公共卫生, 2019, 35(3): 382-385. doi: 10.11847/zgggws1121010
引用本文: 孟灿, 孙成昊, 商磊. PM2.5对慢性阻塞性肺疾病发生发展影响及药物治疗研究进展[J]. 中国公共卫生, 2019, 35(3): 382-385. doi: 10.11847/zgggws1121010
Can MENG, Cheng-hao SUN, Lei HANG. Progress in researches on effect of PM2.5 on occurrence and development of chronic obstructive pulmonary disease and medication of the disease[J]. Chinese Journal of Public Health, 2019, 35(3): 382-385. doi: 10.11847/zgggws1121010
Citation: Can MENG, Cheng-hao SUN, Lei HANG. Progress in researches on effect of PM2.5 on occurrence and development of chronic obstructive pulmonary disease and medication of the disease[J]. Chinese Journal of Public Health, 2019, 35(3): 382-385. doi: 10.11847/zgggws1121010

PM2.5对慢性阻塞性肺疾病发生发展影响及药物治疗研究进展

doi: 10.11847/zgggws1121010
基金项目: 辽宁省科学技术计划(2017010365-301);沈阳市科技计划(17-231-1-43)
详细信息
    作者简介:

    孟灿(1997 – ),女,河南驻马店人,本科在读,沈阳医学院15级临床17班

    通信作者:

    商磊,E-mail:shanglei6677@163.com

  • 中图分类号: R1

Progress in researches on effect of PM2.5 on occurrence and development of chronic obstructive pulmonary disease and medication of the disease

  • 摘要: 慢性阻塞性肺疾病(慢阻肺)是一种以气流受限为特征可以预防和治疗的疾病,与肺部对有害气体的异常炎症及免疫反应有关。目前环境问题受到广泛关注,细颗粒物(PM2.5)作为危害严重的环境污染物,其对健康的影响不容忽视。研究表明PM2.5在慢阻肺发生发展的过程中起到重要作用。PM2.5主要通过氧化应激、炎症反应和免疫功能失衡影响慢阻肺的进展。本文从慢阻肺危险因素入手,综述PM2.5对慢阻肺疾病发生发展影响的可能机制,分析不同药物对PM2.5影响下慢阻肺进展的干预, 为慢阻肺的预防与治疗提供新的思路。
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  • 接收日期:  2018-08-30
  • 刊出日期:  2019-03-01

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