Objective  To investigate the incidence and influencing factors of comorbidities among hypertension patients in a cohort established among workers in an enterprise – Jinchang Cohort, and to provide references for prevention and management of comorbidities in hypertension patients.

  Methods  The data on 4 551 primary hypertension patients were collected in a baseline survey and subsequent follow-ups were carried out during the period from June 2011 to December 2015 among the participants of Jinchang Cohort with on-the-job and retired workers in a large nonferrous metals and chemical enterprise located in Northwestern China. The incidence of comorbidities in the hypertension patients and their influencing factors were analyzed.

  Results  Among the 4 551 hypertension patients, 325 developed comorbidities during the follow-up of 10 174.90 person-years and the comorbidity incidence density was 31.94/1 000 person years. Of the hypertension patients with comorbidities, 92.00% (299) and 8.00% (26) were detected with only one and two or more hypertension comorbidites. The top three comorbidities of the hypertension patients were stroke, coronary heart disease and diabetes, with the incidence densities of 12.87/1 000 person years, 10.91/1 000 person years and 10.61/1 000 person years, respectively. The results of unconditional multivariate logistic regression analysis demonstrated that aged ≥ 45 years was a risk factor for comorbidities of stroke and coronary heart disease, while with the education of college and above was a protective factor against stroke; aged ≥ 65 years, obesity, abnormal total cholesterol and abnormal triglyceride were risk factors for concurrent diabetes.

  Conclusion  Stroke, coronary heart disease and diabetes are high-risk comorbidities of hypertension and older age is a common risk factor for the three comorbidities among the hypertension patients in the workers of Jinchang Cohort.