Abstract:
Objective To observe the preventive effect of Glycyrehize uralensis fisch on damage of genetic M aterials in male mouse reproductive cells induced by Pb(CH3MCOO)2.
Methods Sperm abnormality test, Chromosome aberration of spermatogonia and unscheduled DNA synthesis(UDS)test in male mouse reproductive cells were used in the study.
Results Glycyrrhiza uralensis fisch inhibited significantly sperm abnormality, chromosome aberration of spermatogonia an UDS in mouse reproductive cells induced by Pb (CH3COO)2(P < 0.01).
Conclusion Glycyrrhiza uralensis fisch shows a protective effect, namely antimutagenesis, on injury of genetic materials in reproductive cells of male mouse.