Abstract:
Objective To explore the effects of octachlorodipropyl ether (S2)on chromosome aberration in CHL Cells.
Methods To deter mine the IC50 of S2 on CHL cells, then to establish the scope of doses acco rding to the IC50 and to do cells Chromosome aberration.According to the standard positive response the results were judged.
Results Marginal positive response was found at 24 h after the treatment with S2.Positive responses were found at 48h after treatment or at 6 h after the addition of S-9 mixture.
Conclusion S2 could induce Chromosome aberration in CHL cells.