江苏省农村居民结核病危险因素病例对照研究

吕华坤; 许卫国; 王蓓; 陈永弟; 朱永东; 陈亚飞

江苏省农村居民结核病危险因素病例对照研究

Case-control study on risk factors of pulmonary tuberculosis in rural area of Jiangsu

摘要

摘要:
目的了解江苏省农村结核发病危险因素, 为结核病控制提供依据。
方法采用1:1配对病例对照方法, 分层整群抽取病例和对照各318人进行问卷调查, 计算OR值和95%CI, 并用条件Logistic回归模型进行多因素分析。
结果在单因素分析中, 人均收入、住房类型、人均住居面积、膳食营养(鸡蛋、肉类)、劳动疲乏、经济负担重、有负性事件、结核相关疾病史、吸烟、有结核病(TB)接触史等因素的OR值分别为0.726, 0.649, 0.823, 0.913, 0.906, 1.849, 2.027, 3.867, 2.355, 1.389, 3.599;P均 < 0.05.在多因素分析中, 人均收入低、家庭经济负担重、劳动疲劳、有结核相关疾病史、有负性事件、有TB接触史是影响农村结核病的主要因素。
结论加强结核病人发现、治疗、管理, 并针对其他危险因素采取控制措施对降低农村疫情有重要意义。

Abstract:
Objective To explore risk factors of pulmonary tuberculosis (PTB) among peasants in Jiangsu province.
Methods Using pair matched case-control study, 318 PTBs and 318 controls(pairs matched for age, sex and location) were randomly sampled from countrymen in 3 selected countries; subjects were face-to-face interviewed by trained personals; data was analyzed with conditional logistic regression; ORs of relevant factors were calculated.
Results Single-variable analysis showed that capita-income, type of house, housing area per member, nourishment(meat, eggs), fatigue after working, heavy economic burden, negative events, catching relevant disease, smoking, history of exposure to PTB were associated with incidence of PTB, with ORs of 0.726, 0.649, 0.823, 0.913, 0.906, 1.849, 2.027, 3.867, 2.355, 1.389, 3.599, all P < 0.05, but all factors except for smoking, type of house, housing area per member entered into multiple regression model.
Conclusion The epidemic situation of PTB would be controlled with well-managed PTB and with measures against other risk factors.

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