高级检索
尹学哲, 全吉淑, 安昌善. 大豆胚轴对糖尿病大鼠抗氧化活性的影响[J]. 中国公共卫生, 2004, 20(11): 1293-1294.
引用本文: 尹学哲, 全吉淑, 安昌善. 大豆胚轴对糖尿病大鼠抗氧化活性的影响[J]. 中国公共卫生, 2004, 20(11): 1293-1294.
shu
YIN Xue-zhe, QUAN Ji-shu, AN Chang-shan. Effect of soybean hypocotyl on superoxide dismetase of diabetic rats[J]. Chinese Journal of Public Health, 2004, 20(11): 1293-1294.
Citation: YIN Xue-zhe, QUAN Ji-shu, AN Chang-shan. Effect of soybean hypocotyl on superoxide dismetase of diabetic rats[J]. Chinese Journal of Public Health, 2004, 20(11): 1293-1294.
shu

大豆胚轴对糖尿病大鼠抗氧化活性的影响

Effect of soybean hypocotyl on superoxide dismetase of diabetic rats

    摘要
  • 摘要:
      目的   研究大豆胚轴提取物对糖尿病大鼠血及肝脏过氧化脂质(LPO)水平、丙二醛(MDA)含量及超氧化物歧化酶(SOD)活性的影响。
      方法   给糖尿病大鼠喂饲添加20g/kg大豆胚轴提取物的饲料20周后, 分离血清, 制备肝匀浆。采用八木变法测定过氧化脂质含量, 采用硫代巴比妥酸法测定MDA含量, 采用黄嘌呤氧化酶法测定SOD活力。
      结果   食用大豆胚轴提取物的糖尿病大鼠, 其血清LPO水平和MDA含量显著降低, 肝脏及血清SOD活性明显升高。
      结论   大豆胚轴提取物可降低糖尿病大鼠肝脏及血清中脂质过氧化程度和提高SOD活性, 对糖尿病及其并发症的发生和发展起有效的防治作用。

     

    Abstract:
      Objective   To investigate the effect of soybean hypocotyl extract on lipid peroxide(LPO), malondialdehy de (MDA) and super oxide dismutase (SOD)of blood and liver in diabetic rats.
      Methods   Diabetic rats were given diet containing 20 g/kg of soybean hypocotyl extract for 20 weeks, and then blood LPO was measured by colorimetric method, MDA was measured by thiobarbituric method, and SOD activity was investigated by xanthine oxidase method.
      Results   After 20 weeks of experiment, serum LPO and MDA contents were significantly decreased, and SOD activities in serum and liver were increased noticeably.
      Conclusion   Soybean hypocotyl extract had the function of decreasing blood LPO and MDA contents, and increasing serum and hepatic SOD activities, thus it may be useful in prevention and treatment of diabetes mellitus and diabetes-associated diseases.

     

    • HTML全文
    • 参考文献(5)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回