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周玲, 王劲松, 成金罗, 沈默宇. 2型糖尿病家系危险因素Logistic回归分析[J]. 中国公共卫生, 2004, 20(11): 1304-1305.
引用本文: 周玲, 王劲松, 成金罗, 沈默宇. 2型糖尿病家系危险因素Logistic回归分析[J]. 中国公共卫生, 2004, 20(11): 1304-1305.
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ZHOU Ling, WANG Jin-song, CHENG Jin-luo, . Logistic regresssion of risk factors in type 2 diabetes mellitus pedigrees[J]. Chinese Journal of Public Health, 2004, 20(11): 1304-1305.
Citation: ZHOU Ling, WANG Jin-song, CHENG Jin-luo, . Logistic regresssion of risk factors in type 2 diabetes mellitus pedigrees[J]. Chinese Journal of Public Health, 2004, 20(11): 1304-1305.
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2型糖尿病家系危险因素Logistic回归分析

Logistic regresssion of risk factors in type 2 diabetes mellitus pedigrees

    摘要
  • 摘要:
      目的   研究家系人群中2型糖尿病(T2DM)的危险因素, 为制定干预措施提供依据。
      方法   利用葡萄糖耐量试验(OGTT)、PCR-RFLP和免疫法排除其他类型后确定了115个2型糖尿病家系, 通过问卷调查和实验室检查收集危险因素的情况, 并采用Logistic回归分析方法对新老2型糖尿病患者和糖耐量低减(IGT)患者危险因素进行分析。
      结果   糖尿病患者的多因素分析显示, T2DM患者的年龄(OR=1.043, 95%CI1.024~1.062)、高血脂史(OR=4.471, 95%CI2.149~9303)、高血压史(OR=2.075, 95%CI1.001~4.301)和腰臀比超标(OR=1.809, 95%CI1.00~4.301)是独立的危险因素, 而新诊断患者仅高血压史(OR=6.068, 95%CI1.697~2.1689)是独立的危险因素, IGT患者的年龄(OR=1.398, 95%CI1.138~1.717)是危险因素.
      结论   在本研究人群中, 高血压、年龄、中心性肥胖可能是2型糖尿病的危险因素。

     

    Abstract:
      Objective   To explore the risk factors of type 2 diabetes mellitus in T2DM pedigrees.
      Methods   One hundred and fifteen pedigrees of type 2DM were diagnosed with OGTT, PCR-RFLP, GAD and ICA512.Risk factors were analyzed by Logistic regression.
      Results   Hypertension(OR=2.075, 95% CI1.001-4.301), hyperlipidemia(OR=4.471, 95% CI2.149-9.303), high waist hip ratio(OR=1.809, 95% CI1.001-4.301)and age(OR=1.043, 95% CI1.024-1.062), were significant in multiple-regression of risk factors in T2DM. In new diagnosed T2DM, hypertension(OR= 6.068, 95%CI1.697-2.1689)was significant.Age(OR=1.398, 95% CI1.138-1.717)was significant in IGT.
      Conclusion   Hypertension, age and visceral obesity were risk factors of T2DM probably.

     

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