北京市新生儿乙肝疫苗免疫策略成本效益分析
Analysis on cost-benefit for infant hepatitis B vaccine immunization strategy in Beijing
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摘要:目的 分析北京市新生儿乙肝疫苗免疫策略所取得的经济效益。方法 以北京市疾病预防控制中心报告资料为基础, 采用在自然人群中分层多级抽样和医院内随机抽样相结合的方法, 收集HBV感染相关肝病患者和表面抗原携带者作为费用调查的对象, 运用成本效益分析方法进行综合评价。结果 现行北京市新生儿乙肝疫苗免疫策略使得1992年出生的新生儿90776人一生中避免发生急性乙肝1779例、慢性乙肝1507例、乙肝后肝硬化381例、肝癌1244例、表面抗原携带3359例。可获得8583.37万元的净效益, 效益成本比为13.33。结论 北京市新生儿乙肝疫苗免疫策略可获得巨大的经济效益, 应继续巩固和完善该策略。Abstract:Objective To demonstrate economic benefit of the current strategy for infancy hepatitis B vaccine immunization with the credible data from the disease surveillance of Beijing Disease Control Center.Methods To adopt both methods of multistage sampling and random sampling in the communities and the hospital of Beijing areas respectively.The evaluation for the infant hepatitis B immunization strategy used in Beijing since 1990's was conducted with analysis models of costbenefit.Results 85.83 million Yuan net benefit would be obtained compared with the cost of 6.96 million Yuan for the vaccination.The BCR was 13.33.Conclusion The current immunization strategy of infant hepatitis B vaccination in Beijing would acquire huge economic benefit and it should be consolidated.
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