Objective   To explore the fetation adverse effects of hair curling solution and mousse in mice.

  Methods   The pregnant mice were administered in different concentrations hair curling solution and mousse.The general status of dams and fetus were observed.

  Results   In the hair curling solution group, there were significant reduction in mean dams body weight and increase in skeletal malformation of fetus.In both hair curling solution and mousse groups, at high and low dose, the mean body weight, average body length, tail length, living rate of fetus significantly decreased, however the rate of absorption and the death rate of the embryos increased significantly as compared with control group.At the high dose of hair curling solution and mousse, the exterior malformation rate of fetus was higher than that of control group.The viscera malformation of fetus was not discovered.

  Conclusion   Both hair curling solution and mousse had fetation adverse effects on pregnant and fetal mouse.