类风湿关节炎危险因素的病例对照研究

沈冲; 叶冬青; 翟金霞; 黄芬; 李向培

类风湿关节炎危险因素的病例对照研究

Case-control study on risk factors for rheumatoid arthritis

摘要

摘要:
目的探索影响类风湿关节炎(RA)发病的危险因素。
方法以120例确诊的类风湿关节炎患者为病例组, 以同地区120名健康者按性别、年龄(±3岁)进行1:1配对进行病例对照调查。
结果单因素分析结果发现, RA与环境、个体、感染因素以及女性相关因素等关系密切; 男性RA患病的危险因素明显少于女性(女性相关因素除外), 进行逐步Logistic回归分析, 结果得到进一步证实。
结论 RA与多种因素相关。口味偏淡、性格开朗为男女RA发病的共同相关因素; 女性RA发病的危险因素多于男性。

Abstract:
Objective To research risk factors of Rheumatoid Arthritis(RA).
Methods A 1:1 case-control study on 120 RA patients were matched with 120 healthy controls by sex and age(not beyond ±3 years old).Logistic regression models were used to analyze the relationships between factors and RA.
Results RA had some relations with multifactor.Tasteless, broad-mined, easy agitating, stream nearby were the same related factors for male and female RA patients.Moreover, as a protective factor, broad-mined entered the Logistic regression equation stepwise.Risk factors for male RA patients were less than female's, but except factors related female.Furthermore results of Logistic stepwise regression analyses confirmed this.
Conclusion Broad-mined and tasteless were the same related factors for male and female RA patients.Female RA patients had some relations with more risk factors than male.

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