诺瓦克样病毒抗体水平及其相关因素研究

戴迎春; 聂军; 张绪富; 李志峰; 刘翼; 俞守义; XiJiang

诺瓦克样病毒抗体水平及其相关因素研究

Serum antibodies against Norwalk-like viruses and concerned factors

摘要

摘要:
目的了解某军校学员诺瓦克样病毒抗体水平, 同时调查分析与血型、入学前家庭所在地等的关系。
方法利用酶联免疫吸附试验检测血清中的诺瓦克样病毒rNV、rMX和r387特异性IgG抗体水平。
结果 rNV、rMX和r387IgG抗体总检出率分别为88.9%, 54.1%和90.0%。其中rMX抗体阳性率不同血型之间存在显著性差异(P < 0.05), 以O型抗体阳性率最高62.5%(115/184), B型最低49.1%(160/216), 而rNV和r387抗体阳性率未见显著性差异. 不同入学前家庭所在地3种抗体阳性率均有显著性差异, 其中以农村籍学员抗体阳性率最高, 城市最低。
结论该军校人群中诺瓦克样病毒感染普遍, 血型及入学前家庭所在地可能是影响诺瓦克样病毒抗体水平的因素。

Abstract:
Objective To investigate serum antibodies against Norwalk-like viruses of a military university and the concerned factors; such as blood type and the family locus before enrolling.
Methods Serum specimens are tested by an indirect enzyme-linked immunosorbent assay(ELISA)for specific Ig G respectively to rNV, rMX and r387.
Results The seropreva-lence is 88.9% for rNV, 54.1% for rMX and 90.0% for r387.There is significant difference between blood types for rMX of which the type O prevalence is the highest(62.5%), and the type B is the lowest(49.1%).And there is significant difference between the family locus before enrolling for rNV, rMX and r387.
Conclusion The data indicates that infections of Norwalk-like viruses in the military university are very common.And blood type and family locus before enrolling may be the risk factors of the serum antibodies of Norwalk-like viruses.

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