HIV与输血传播病毒的母婴传播的调查
Survey on mother-to-child transmission of HIV and TTV
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摘要:目的 了解艾滋病高发区HIV与输血传播病毒(TTV)母婴传播情况。方法 对华中地区某艾滋病高发农村228名母亲及其年龄小于15岁的子女180名进行入户流行病学调查, 采集静脉血检测抗HIV、抗TTV, 回顾性分析2种病毒的母婴传播特点。结果 82例HIV阳性母亲1993年后生的103名儿童中, 39例HIV阳性, 母婴传播率为37.9%;59例抗TTV阳性母亲所生的76名儿童中, 5例抗TTV阳性, 母婴传播率为6.6%。结论 HIV与TTV在当地均存在母婴传播; 母婴传播是儿童感染HIV的主要途径。未对HIV流行地区高危生育期妇女进行有效的HIV监测与咨询, 未及时采取有效干预措施是造成该地区儿童感染HIV的主要原因, 亟需制定实施相应的对策, 控制HIV进一步蔓延, 保护HIV感染高发区妇女及儿童的健康。Abstract:Objective To estimate the mother-to-child transmission of HIV and TTV in highly epidemic rural area of AIDS.Methods 228 high-risk women of childbearing age and 180 children aged 0-14 years were investigated.their medical histories of blood donation or transfusion are collected, blood samples are taken and serum are separated for anti-HIV and anti-TTV test.Results 39 HIV infected cases are found among 103 children who are born by HIV-positive mother after 1993.the number of children infected with HIV through vertical transmission increases from 1993 to 2001.5 antiTTV is positive among 76 children who born by anti-TTV positive mothers.Conclusion Mother-to-child transmission is one tranmisson route of HIV and TTV in highly epidemic rural area of AIDS.Vertical transmission of HIVis the major route for children with HIV/AIDS.the main reason leading to children HIV infection is the lack of prenatal HIV counseling and testing for the high-risk women of childbearing age and lake of interventions.the counter measures must be taken to control the further transmission of AIDS in order to protect the health of women and children in highly epidemic areas of AIDS.
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