Abstract:
Objective To study the effect of laminaria hemicellulose on thrombus formation.
Methods The occlusion time and the weight of thrombus were compared between laminaria hemicellulose group and control group respectively through three rat models of thrombus formation after laminaria hemicellulose was injected intraperitoneally(i.p)for three days.
Results Both low dose group of laminaria hemicellulose(20 mg/kg)and high lose group of laminaria hemicellulose (100 mg/kg)can obviously prolong the occlusion time and decrease the weight of thrombus.
Conclusion Laminaria hemicellulose can inhibit the thrombus formation in rats.