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梁戈玉, 浦跃朴, 尹立红. 南京市肺癌环境危险因素的病例对照研究[J]. 中国公共卫生, 2004, 20(3): 260-261.
引用本文: 梁戈玉, 浦跃朴, 尹立红. 南京市肺癌环境危险因素的病例对照研究[J]. 中国公共卫生, 2004, 20(3): 260-261.
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LIANG Ge-yu PU Yue-pu, YIN Li-hong, . Case-control study on environmental risk factors of lung cancer in Nanjing population[J]. Chinese Journal of Public Health, 2004, 20(3): 260-261.
Citation: LIANG Ge-yu PU Yue-pu, YIN Li-hong, . Case-control study on environmental risk factors of lung cancer in Nanjing population[J]. Chinese Journal of Public Health, 2004, 20(3): 260-261.
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南京市肺癌环境危险因素的病例对照研究

Case-control study on environmental risk factors of lung cancer in Nanjing population

    摘要
  • 摘要:
      目的   探讨近年来南京市肺癌发生的环境危险因素。
      方法   对南京市63例原发性肺鳞癌和89例原发性肺腺癌进行1:1配对病例-对照研究,并用条件Logistic回归模型分析危险因素。
      结果   慢性支气管炎史、吸烟指数是肺鳞癌发生的环境危险因素,其OR值分别为8.55,2.35;人群归因危险度分别为18.22%,58.80%;综合人群归因危险度为0.6871.慢性支气管炎史、肺结核史、不良烹调习惯、煤炉使用年限、家族肿瘤史是肺腺癌发生的环境危险因素,OR值分别为5.16,412,2.91,2.02,2.59;人群归因危险度分别为8.15%,11.91%,27.30%,29.98%,10.35%;综合人群归因危险度为0.6306。
      结论   肺鳞癌、腺癌的发病分别与多种环境因素有关,应积极控制环境危险因素,以减少肺癌的发生率。

     

    Abstract:
      Objective   To study the environmental!risk factors of lung cancer in Nanjing population.
      Methods   A 1:1 match case-control study was carried out,which involved 63 cases of primary pulmonary squamous cell carcinoma and 89 cases of pulmonary adenocarcinoma.The environmental risk factors were analyzed by conditional logistic regression model.
      Results   Chronic bronchitis and quantity of smoking were found to be risk factors to lung squamous cell carcinoma.The OR value was 8.55,2.35,respectively,and population attributable risks(PAR)for each of them was 18.22%,58.80%,respectively,the total PAR was 68.71%.The risk factors related to lung adenocarcinoma were chronic bronchitis,the history of pulmonary tuberculosis,bad cooking habituation,use of coal stove and family histoty of cancer.The respective OR value was 5.16,4.12,2.91,2.02,2.59,and PAR was 8.15%,11.91%,27.30%,29.98%,10.35%,respectively.Summary PAR for the five factors above was 63.06%.
      Conclusion   The development of pulmonary squamous cell carcinoma and adenocarcinoma was related with various environmental factors respectively.Strengthening the control of the environmental risk factors was suggested to reduce the incidence of lung cancer.

     

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