多重填充方法评估日本血吸虫病感染率

Use of multiple imputation to assess infection rate of schistosomisasis japonicum

摘要:
目的对血吸虫病监测点的粪检感染率进行评估。
方法从全国12个先经血检过筛后再用粪检进行确诊的监测点中随机抽取一个。采用统一的问卷调查居民与血吸虫病感染有密切关系的因素, 采用多重填充方法对血吸虫病粪检感染率进行估计。
结果监测点居民粪检感染率约为20%, 间接血凝试验(IHA)检测阴性者415人中有8%左右的居民被漏检。
结论居民血吸虫病粪检感染率被低估了5%左右。

Abstract:
Objective To assess the schistosomiasis infection rate of the surveillance spots.
Methods One surveillance spot was sampled at random from the twelve national surveillance spots, in which resident were screened by blood detection first and then were diagnosed by stool examination.The factors related with schistosomiasis infection were survey be questionnaire, and the infection rate of schistosomiasis was assessed by multiple imputation.
Results In Quanxing village, the proportion of stool-positive resident assessed by the multiple imputation was about 20% and the proportion of resident who would show positive in the underwent stool examination was 8 percent among the 415 resident who were negative by IHA detection.
Conclusion The proportion of stool-positive resident was underestimated in Quanxing village, and the underestimated proportion was about 5 percent.