Objective   To investigate the effects of fluo ride dentifrice on children in the high fluorine regions.

  Methods   Based on the fluorine concent ration of drinking water, the children(10-14 years old)were divided into high fluorine group and low fluorine group, and then using fluoride dentifrice group and no-using fluoride dentifrice group, then to check up every status of dental fluorosis and dental caries.

  Results   (1) The prevalence of dental caries of the childrens permanent teeth of drinking high fluorine water group was higher than that of drinking low fluorine water group, there was not significant difference.(2)The prevalence of dental fluorosis of the children drinking low fluorine water was no difference no matter whether using fluoride dentifrice or not.(3)The prevalence of dental fluorosis of using fluoride dentifrice of the children drinking high fluorine water was 2.16 times of that of no using fluoride dentifrice group, was over 3 times of that of the child drinking low fluorine water.

  Conclusion   Use of fluoride dentifrice in high fluoride regions could increase prevalence of dental fluorosis.