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逄增昌, 翟耀明, 汪韶洁, 彭向东, 薄涛, 闫克乐, 张云, 李晓斐, 苑妹. 双生子A型人格与高血压及血生化指标研究[J]. 中国公共卫生, 2003, 19(6): 655-656.
引用本文: 逄增昌, 翟耀明, 汪韶洁, 彭向东, 薄涛, 闫克乐, 张云, 李晓斐, 苑妹. 双生子A型人格与高血压及血生化指标研究[J]. 中国公共卫生, 2003, 19(6): 655-656.
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PANG Zeng-chang, ZHAI Yao-ming, WANG Shao-jie, . Study on relationship of type A personality of twins with hypertension and biochemical index in serum[J]. Chinese Journal of Public Health, 2003, 19(6): 655-656.
Citation: PANG Zeng-chang, ZHAI Yao-ming, WANG Shao-jie, . Study on relationship of type A personality of twins with hypertension and biochemical index in serum[J]. Chinese Journal of Public Health, 2003, 19(6): 655-656.
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双生子A型人格与高血压及血生化指标研究

Study on relationship of type A personality of twins with hypertension and biochemical index in serum

    摘要
  • 摘要:
      目的   了解双生子A型人格与高血压及血液生化指标的关系。
      方法   利用遗传流行病学方法对青岛市89对24岁以上双生子(同卵55对, 异卵34对)进行调查。并进行A型人格测试, 以比较同卵与异卵双生子A型人格得分的相关程度、A型人格及血压的一致性。推测遗传与环境因素对A型人格的影响, A型人格与高血压的关系, 并探讨血液生化指标与A型人格的关系。
      结果   经KAPPA一致性检验, 同卵(MZ)双生子之间A型人格存在着显著的一致性(P < 0.001), 而异卵(DZ)双生子之间的一致性无显著性差异(P=0.802)。同时, MZ双生子之间A型人格和血压也存在显著的一致性(P < 0.001), 而DZ双生子之间A型人格和血压无明显一致性(P=0.102)。有A型人格的双生子血压的收缩压明显高于非A型人格的双生子(P < 0.05)。许多生化指标与A型人格因素相关, 但是所计算出的相关系数大都小于0.30, 属于弱相关。
      结论   MZ双生子A型人格及高血压之间存在着显著的一致性, 而这种一致性在DZ双生子表现不明显。A型人格是高血压的危险因素之一。A型人格与所研究血液基本生化指标之间相关较弱。

     

    Abstract:
      Objective   To study on the relationship of type A personality of twin serum biochemical index of hypertension.
      Methods   89 twin pairs (MZ: 55, DZ: 34) older than 24 in Qingdao was investigated with genetic epidemiological methods. Type A personality of the twins was tested to study the correlation of the scores in MZ and DZ twins, so that the effect of genetic and environmental factors on type A personality can be studied. The relationship between type A personality and hypertension, type A personality and some serum biochemical index were also discussed.
      Results   Significant agreement of type A personality in MZ twins was found (P < 0.001), such agreement was not found in DZ twins (P=0.802). Also agreement of type A personality and hyper tension was significant in MZ (P < 0.001), not significant in DZ (P=0.102). The systolic blood pressure (SBP) was higher for twins with type A personality than non-A personality twins. Some serum biochemical index was correlated with type A personality, but most of the correlation coefficients were lower than 0.30.
      Conclusion   A greement of type A personality and hypertension was significant in MZ, not significant in DZ. Type A personality was a risk factor for hypertension. The correlation between type A personality and basic serum biochemical index was weak.

     

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