曲靖市健康人群麻疹中和抗体监测分析

速存芬; 朱阳华; 田炳均; 徐闻

曲靖市健康人群麻疹中和抗体监测分析

Survey on measles neutralization antibody level in healthy population of Qujing city

摘要

摘要:
目的为进一步掌握曲靖市健康人群麻疹抗体水平, 为控制麻疹采取相应措施提供科学依据。
方法随机抽取6个县市(区)4个年龄组205名健康人群, 应用中和试验方法进行麻疹中和抗体检测。
结果麻疹中和抗体阳性率94.63%, GMT为1:3494, 抗体滴度达保护水平(≥1:16)占77.56%, 不同地区、不同年龄、麻疹免疫史、麻疹病史GMT有显著性差异, 阳性率无显著性差异。
结论曲靖市育龄妇女对麻疹病毒有一定的免疫力, 我市麻疹疫苗初免为8月龄是合适的; 个别地区计划免疫存在薄弱环节, 人群保护抗体水平低, 是我市麻疹发病上升的重要原因。

Abstract:
Objective To investigate measles neutralization antibody level in healthy population of Qujing city for providing scientific evidence for the implementation of measles control measures.
Methods A total of 205 serum samples of healthy persons composed of 4 age groups were randomly collected from 6 cunties or cities(districts)to detect measles neutralization antibodies.
Results Measles neutralization antibody positive rate was 94.63% with a GMT of 1:34.94.77.56% people's neutralization antibody was more than 1:16.Although, GMT had no significant difference among positive rates, there was significant difference among GMTs by regions, age groups, measles immunization history and disease history.
Conclusion Child -bearing women had immunity to measles in certain degree and the schedule that the first dose was given at 8 month of age was suitable.The reason for the raising of measles incidence rate in our city was that there were some weaknesses in the EPI work and that the protective measles antibody level was lower.

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