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李思果, 彭良斌, 黄薇, 王继尧, 魏若飞. 妊娠反应与孕早期碘营养和垂体-甲状腺功能的关系[J]. 中国公共卫生, 2003, 19(1): 37-38.
引用本文: 李思果, 彭良斌, 黄薇, 王继尧, 魏若飞. 妊娠反应与孕早期碘营养和垂体-甲状腺功能的关系[J]. 中国公共卫生, 2003, 19(1): 37-38.
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LI Si-guo, PENG Liang-bin, HUANG Wei, . Relation between morning sickness and iodine nutrition, pituitary-thyroid function during early pregnant stage[J]. Chinese Journal of Public Health, 2003, 19(1): 37-38.
Citation: LI Si-guo, PENG Liang-bin, HUANG Wei, . Relation between morning sickness and iodine nutrition, pituitary-thyroid function during early pregnant stage[J]. Chinese Journal of Public Health, 2003, 19(1): 37-38.
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妊娠反应与孕早期碘营养和垂体-甲状腺功能的关系

Relation between morning sickness and iodine nutrition, pituitary-thyroid function during early pregnant stage

    摘要
  • 摘要:
      目的   揭示妊娠反应对垂体-甲状腺功能的影响。
      方法   收集在市妇幼医院确诊的第12~14周孕早期及同龄婚检妇女血及尿.血碘采用改进的砷铈催化分光光度法, FT4、FrT3、sTSH用化学发光法测定, 妊娠反应采用评分量化。
      结果   47例妊娠反应阳性的血清碘(G)61.2μg/L, 尿碘(G)152.1μg/L, FT4为14.42pmol/L, FrT3/FT4为0.346, sTSH为3.78mU/L, 分别低于和高于妊娠反应阴性组和未孕组(P均 < 0.01), 阳性组尿碘 < 100μg/L有20%及sTSH > 50mU/L有8.6%.除未孕组FT4与FrT3无相关性外, 余下妊娠反应阳性程度与血清碘和FT4及sTSH均有密切相关(r=0.654和r=-0.354, P < 0.01及P < 0.05)。
      结论   妊娠反应对孕早期碘营养代谢、垂体-甲状腺功能减弱有协同作用, 应引起关注。

     

    Abstract:
      Objective   In order to reveal the effects of morning sickness on pituitary-thyroid function.
      Methods   To collect urine and vein blood of early pregnant women(12-14 weeks)and marriage examination women in the Women and Children Hospital of Shenzhen.Iodine in urine was determined by As(Ⅲ)-Ce 4+ catalytic spectrophotometry to measure serum iodine, Automated Chemiluminescence System was used to test FT4、FrT3 and sTSH.
      Results   Serum iodine(G)of 35 pregnant women who had morning sickness was 61.2 g/L, urine iodine was 152.1 g/L, FT4 was 14.42 pmol/L, FrT3/FT4 WAS 0.346, sTSH was 3.78 mU/L.All of them were obviously lower or higher than those of non-morning sickness and non-pregnant group(p < 0 01).Urine iodine of morning sickness group < 100 g/L was 20%, and sTSH > 5 0 mU/L was 8.6%.Correlation was found between serum iodine and FT4, sTSH in morning sickness group except for non-pregnant group(r=0.654 and -0.354, P < 0.01 and P < 0.05).
      Conclusion   Coordination impact was found between metabolism of iodine nutrition and descent of pituitary-thyroid function during early pregnancy, which should be paid attention to.

     

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