富铬酵母提取液降低血糖作用观察

李鹏飞; 张绍维; 孙文娟; 王雨; 叶丽杰

富铬酵母提取液降低血糖作用观察

Effects of chromium-rich brewers yeast on blood sugar in type 2 diabetes patients

摘要

摘要:
目的观察富铬酵母提取液降低2型糖尿病患者血糖的作用.
方法将132例2型糖尿病患者, 其中男性84例, 女性48例, 按性别分层后随机分为实验组与对照组.在原治疗方案不变的条件下, 实验组加服富铬酵母提取液.剂量以每日含铬200g计, 观察3个月后血糖、胰岛素与糖化血红蛋白的变化.
结果口服富铬酵母提取液3个月后, 实验组的血糖、胰岛素与糖化血红蛋白与服用前及对照组比较均显著降低.实验组41%、对照组24%的患者空腹血糖降至7.0 mmol/L以下, 2组比较差异有统计学意义, P < 0.05.
结论富铬酵母提取液具有较好的降低2型糖尿病患者血糖的作用, 作用机制可能是提高胰岛素的生物效应, 或提高胰岛素受体的敏感性, 而不是促进胰岛细胞分泌胰岛素.

Abstract:
Objective To investigate the clinical effects of chromium-rich brewer's yeaston blood sugar which were extracted from saccharomyces cerevisiae byextractive and ultra-filtration.
Methods 132 patients with type 2 diabetes were divided randomly into treatmentgroup and control group.The patients in the treated group took orally chromium-rich brewer's yeastwhich contented 200 Lg chromium/dayexceptfor mer treatproject.3 months later, the levels of FBG, PBG, insulin and HbAIC were measured.
Results The levels of FBG, PBG, insulin and HbAIC in treated group were decreased significantly than those of control group.The frequency of FBG levels under 7.0 mmol/l were 41% in treated group and 24% in contrgroup.
Conclusion Chromium-rich brewer's yeastcan remarkably reduce the blood sugar of type 2 diabetes patients, which may be related to itcan increase the effects of insulin or the sensitivity of receptor, butnotto impr ove the insulin's excretion.

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