Abstract: To determine the prevalence of gout and hyperuricemia among the population in eastern coastline area Provice, the total of 17044 population in Rizhao of Shandong，Dong Ying,Weihai, and Shengli oil field were investigated. The serum uricacid was detected by Uricasetrindr method in a random sample that made up of 384 adult normal people. The results showed that crude prevalence of gout was 0.0352% and standardizell prevalence was 0.0315%，the ratio of standardized-prevalence in males to females was 1:0.415. The mean serum uricacid level was 289.6±76μmol/L in males versus 236.5±63.3μmol/L In felnales There was a slgnlfleant dlffelence between hales anci felnales The prevaalence of hyperuricemia was 5.79% in males and 2.44% in females. The result suggest hat the level of serumuric acid prevalence of hyperuricemia and gout among population of Shandong Province is signifi-candy lower than the cxmresponding level in European, American and Snutheaet Asia.