甲型肝炎减毒活疫苗免疫程序的探讨

The Study on HAV Attenuated Live Vaccire Immune Program

摘要: 52名HAV抗体阴性的儿童，按0.3个月免疫程序，经2针低剂量（5.50lgCCID50/ml）甲型肝炎减毒活疫苗免疫，于第2针接种后7天检测HAV抗体阳转率为100%，抗体效价GMT值为1：14；全部接种儿童的ALT均在正常范围内（2~24μl）；免前HAV抗体阳性的儿童，经2针免疫后，抗体效价增长在2倍以上。

Abstract: The report show the inmunization result of 52 children inmunized with twice HIV attennuated live vaccine which infection titer is as 550kg CCID50/ml respectively at 0.3 mont of The presentive data indicated that HAV antibody response all chillren inmunized is postive The average titer of antibody is 1:8~1:32GMT IS 13.82 The GPT value of all children inm un ized is unchanged(2~24). The group of HAV antibody being positive has the 2 times increasrs Of HAV antibody level after in m unized twice vaccine.