Abstract: We have observed w hole proc;Exlure of infec;tpn in MA-104 vero and ACMK clls A DRV infects cells and producers syncytia 48~72 hours post-infecction syncrytia coutain ADRV specific proteins as demonstrated by inmunostaining but attempts to passage the virus have not been successful This study have observed viral infection of ytolvel andw ould supply ccientific; evidences for ADRV cultivation It's a quastion formaking vacx;ine by cultivation.