广东省1990～1998年登革热流行病学监测分析
Epidemioloeical Surveillance of Dengue Fever in Guangdong Province
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摘要: 为了预防登革热的暴发流行,于1996 年4 月～1998年12 月开展了登革热的流行病学监测,根据以往发生过登革热流行的疫情分析,选择广东省3 个监测点,收集血标本95 份及蚊媒标本6000 余只分别作病原分离,并进一步采用单克隆抗体间接免疫荧光试验和RT- PCR 鉴定;采集监测点健康人血标本1025 份应用间接免疫荧光试验作抗体水平调查。3 个监测点上收集的发热待查患者和蚊媒标本均未能分离出登革病毒。蚊媒监测结果提示:布雷图指数大大超过有效控制指标5 ;全年大部分时间布雷图指数均超过20 以上;血清学调查表明:健康人群抗体水平逐年下降;因此存在登革热暴发流行的潜在危险。Abstract: The epidemiological surveillance of deng ue fever was carried out in parts of Guangdong province from 1996 to December, 1998.It may help to predict early the prevalence of dengue fever and to prevent its Three districts:Foshan city.Shawang town and the town of Ping shi where dengue fever once happened were Chosen.Dengue virus was not found through isolation from boat the sera of unknown feverist patients and the mosquito pools.But, as for mosquitoes, the Breteau index was highly above the effective control limit which is 5.As for seroepidemiology, the dengue antibody level of the healthy mass is decreasing with time.In Pingshi town the local dengue antibody level was even close to zero.So there lies the potential danger of the outbreak of dengue fever.
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