Abstract: A study on the effect of low - level carbon disulphide on the peripheral nerve function of ex posed workers. The electro physiological abnormalities of these w orkers were in accordance with characteristic alteration of primary axonal nerv edamage, which was atype of "dyng back" polyneuropathy, at the same time with some damage on myelin sheath. At the other hand. the damage of nerve caused by carbon disulfide is not palallel in the two sides.The dose- response relationship betw een the exposure to carbon disulfide and the damage of peripheral nerve was demonstrated.The minimum latency of Fwave is a benifical parameter.