Abstract: In order to study the incidence trend and epidemic pattern of Hemorrhagic Fever with Renal Syndrome(HF RS),the incidence and surveillance data of HFRS in Shaoxing City during 1966~1998 was anaiysed.The results showed that the range of incidence rate was 0.29~82.61/100000,the annual average incidence rate was 20.77/100000.Total morbidity rate in 1980s was the highest and declined slowly in 1990s.Cases of HFRS cccured sporadically,but the distribution had a obviously clustering.The season distribution of HFRS was double peak pattern in whole city.The case number of fall and witer peak was decreased when compared with the past years.The peak time delayed,and had a degenerative trend.The major sources of infection of HFRS were Apodemus agrarius and Rattus norvegicus.The infectious focux was mixed type with the main type of Apodemus agrarius.The authors suggested exterminating rat and inoculation were effective measures in the control of HFRS.