Abstract: Objective To analyze hospitalization expense and its main influencing factors in angina patients and to provide references for controlling the excessive increase in medical expense. Methods A retrospective study was conducted based on a random sample of 5 826 hospitalized patients with medical insurance from January 2004 to December 2007 in Tianjin city. Results The mean hospitalization cost was 14 793.01 RMB yuan per patient from 2004 to 2007.The mean hospitalization cost was 4 329.77 RMB yuan per patient in first-grade hospital,7 427.15 RMB yuan per patient in secondgrade hospital,and 16 524.95 RMB yuan per patient in third-grade hospital.The items of hospitalization cost of angina patients with medical insurance were as follows:medicine(3 807.89 RMB yuan,25.74%),examination(1 706.71 RMB yuan,11.54%),treatment(1 680.25 RMB yuan,11.36%),surgery(269.75 RMB yuan,1.82%),bedding(414.64 RMB yuan,2.80%),materials(6 828.82 RMB yuan,46.16%),transfusion(12.70 RMB yuan,0.09%),component transfusion (38.21 RMB yuan,0.26%),and other costs(34.02 RMB yuan,0.23%).The results of multiple linear regression showed that the patients in higher grade hospital,with longer hospitalization,and having operation treatment had much more cost than other patients.The female and elder patients had less cost. Conclusion Gender,age,grade of hospital,time of hospitalization,times of admission and operation are the influencing factors of the hospitalization cost for angina patients in Tianjin city.