Abstract: Objective To explore the situation of stress and its relationship with personality among doctor students. Methods Totally 119 students were selected from 5 cities and asked to fill in questionnaires of stress and personality with simple random and convenience sampling. Results There were significant differences among the five dimensions (F=34.002,P=0.000).Unmarried doctor's romantic pressure was significantly higher than the married;the total and study pressure of doctors studying at their own expenses were significantly higher than those at public expense(F₁=6.899, p₁=0.000;F₂=1.916,p₂=0.002).The grade had significant effect on the stress in the students(F=1.753,P=0.184). The relevances among all dimensions of personality and pressure were not consistent. Conclusion Among doctor students, the stress of marriage is the most serious,followed by the schoolwork stress,economic stress and the employment stress,and the intepersonal relation stress is the mildest.Marital status,at one's own expense or at public expense,and grade affect the stress at different extent.There are various effects of stress on different dimensions of personality.