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林茜, 周令. 大连市成人麻疹病例发病特征及影响因素[J]. 中国公共卫生, 2018, 34(9): 1292-1294. DOI: 10.11847/zgggws1113624
引用本文: 林茜, 周令. 大连市成人麻疹病例发病特征及影响因素[J]. 中国公共卫生, 2018, 34(9): 1292-1294. DOI: 10.11847/zgggws1113624
Qian LIN, Ling ZHOU. Incidence characteristics and influencing factors of measles among adults in Dalian city: a case-control study[J]. Chinese Journal of Public Health, 2018, 34(9): 1292-1294. DOI: 10.11847/zgggws1113624
Citation: Qian LIN, Ling ZHOU. Incidence characteristics and influencing factors of measles among adults in Dalian city: a case-control study[J]. Chinese Journal of Public Health, 2018, 34(9): 1292-1294. DOI: 10.11847/zgggws1113624

大连市成人麻疹病例发病特征及影响因素

Incidence characteristics and influencing factors of measles among adults in Dalian city: a case-control study

  • 摘要:
      目的  分析大连市 ≥ 15岁成人麻疹病例发病特征,探索该人群发病影响因素,为消除麻疹提供科学依据。
      方法  采用描述流行病学方法对2014年成人麻疹流行病学特征进行分析,采用1 : 1配比病例对照研究方法,比较病例组与对照组居住地区、户籍、外出史、就诊史、接触史、免疫史等可能影响因素的差异。
      结果  2014年成年人麻疹报告113例,占总病例数的37.42 %。成人病例中,以城乡结合部居多,发病年龄以25~34岁成人居多,发病的季节高峰在4 — 5月份。多因素分析结果显示,城乡结合部居住(OR = 1.623,95 % CI = 1.099~2.396)、非本市户籍(OR = 3.148,95 % CI = 1.550~6.393)、外出史(OR = 3.468,95 % CI = 1.015~11.856)、就诊史(OR = 10.307,95 % CI = 2.854~37.228)、接触史(OR = 10.236,95 % CI = 1.992~52.601)为成人麻疹发病的危险因素,免疫史(OR = 0.107,95 % CI = 0.023~0.505)为保护因素。
      结论  接触史、就诊史、外出史、非本市户籍、城乡结合部居住是大连市成人麻疹发病的影响因素,接种疫苗则为保护性因素。

     

    Abstract:
      Objective  To analyze epidemiological characteristics and influencing factors of measles among adult residents in Dalian city of Liaoning province and to provide evidences for measles elimination.
      Methods  We collected data on measles cases aged ≥ 15 years and reported during 2014 and recruited age and incidence time matched (1 : 1) controls with diseases other than measles and rubella in Dalian city. Differences in residence, census register, travelling history, and histories of taking medical service, related exposure, and immunization were compared between the cases and the controls.
      Results  A total of 113 adult measles cases were reported, accounting for 37.42% of all the cases reported in the city during the year. The majority of the cases were the residents aged 25 – 34 years, living in urban-rural fringe areas, and having the incidence between April and May. Multivariate logistic analysis revealed that the risk factors for the incidence of measles included living in urban-rural fringe area (odds ratio OR= 1.623, 95% confidence interval 95% CI: 1.099 – 2.396), with no local census register (OR = 3.148, 95% CI: 1.550 – 6.393), travelling history (OR = 3.468, 95% CI: 1.015 – 11.856), history of seeking medical service (OR = 10.307, 95%CI: 2.854 – 37.228), and the history of contacting with a measles patient (OR = 10.236, 95% CI: 1.992 – 52.601); while, with the history of measles vaccine inoculation was a protective factor (OR = 0.107, 95% CI: 0.023 – 0.505).
      Conclusion  The risk factors for measles incidence are the history of contacting with a measles patient, histories of seeking medical service and travelling, without local census register, and residing in an urban-rural fringe area and having measles vaccine inoculation is a protective factor for adult residents in Dalian city.

     

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