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李斯斯, 徐永芳, 农丽萍, 邓小芳, 姚敏, 黄晓芳, 杨曦. 广西南宁HIV感染长期不进展者流行病学特征分析[J]. 中国公共卫生, 2018, 34(12): 1608-1611. DOI: 10.11847/zgggws1118198
引用本文: 李斯斯, 徐永芳, 农丽萍, 邓小芳, 姚敏, 黄晓芳, 杨曦. 广西南宁HIV感染长期不进展者流行病学特征分析[J]. 中国公共卫生, 2018, 34(12): 1608-1611. DOI: 10.11847/zgggws1118198
Si-si LI, Yong-fang XU, Li-ping NONG, . Epidemiology characteristics of long-term nonprogressors among HIV-infected people in Nanning city of Guangxi[J]. Chinese Journal of Public Health, 2018, 34(12): 1608-1611. DOI: 10.11847/zgggws1118198
Citation: Si-si LI, Yong-fang XU, Li-ping NONG, . Epidemiology characteristics of long-term nonprogressors among HIV-infected people in Nanning city of Guangxi[J]. Chinese Journal of Public Health, 2018, 34(12): 1608-1611. DOI: 10.11847/zgggws1118198

广西南宁HIV感染长期不进展者流行病学特征分析

Epidemiology characteristics of long-term nonprogressors among HIV-infected people in Nanning city of Guangxi

  • 摘要:
      目的  了解广西壮族自治区南宁市艾滋病病毒(HIV)感染者中长期不进展者(LTNP)的流行病学特征及影响因素。
      方法  从国家艾滋病综合防治信息管理系统下载1996 — 2014年8月31日的历史卡片,选取报告时间≥10年(即2004年及以前报告)、现住址为南宁的574例艾滋病病例进行描述性流行病学分析及logistic回归分析。
      结果  符合入选标准的研究对象574例,根据严格定义归类为LTNP 202例(1.6 %, 202/12 545),可随访并存活病例95例。多因素logistic回归分析显示年龄、感染途径、抗病毒治疗情况、随访状态是LTNP分布的影响因素。
      结论  南宁市存在一定比例的LTNP,为艾滋病长期不进展状态的前瞻性研究和相关性研究提供基础数据。

     

    Abstract:
      Objective  To analyze epidemiology characteristics and determinants of long-term nonprogressors (LTNP) among human immunodeficiency virus (HIV)-infected people in Nanning city of Guangxi Zhuang Autonomous Region (Guangxi).
      Methods  Data on HIV/AIDS patients registered from 1996 to August 31st, 2014 were retrieved from National Information Management System for Comprehensive HIV/AIDS Prevention and Control; then the 574 HIV/AIDS patients registered before 2004 and with the reported residence address in Nanjing city were included in the study. Descriptive epidemiology methods and logistic regression analysis were adopted in the study.
      Results  Of the 574 HIV/AIDS patients, 202 were categorized as LTNP according to the strict definition of LTNP, accounting for 1.6% of all registered HIV/AIDS patients (12 545) during the 19-year period in the region. Among the 202 LTNP, 95 were alive and followed up. The results of multivariate logistic regression analysis revealed that age, route of the infection, status of antiretroviral therapy, and whether being followed-up were the influencing factors of LTNP.
      Conclusion  A portion of long-term nonprogressors exist among HIV-infected patients in Nanning city and the result provides a data set for further relevant researches.

     

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