Abstract: Dyslexia includes developmental dyslexia and acquired dyslexia. Developmental dyslexia refers that although some children have normal intelligence, emotion, equal educational and socio-cultural opportunities, they have particular difficulties in reading and spelling, such as poor verbal communication skills, often typo, reading plus words, missing words, not understanding the meaning of the contents of the reading. We reviewed the progress in the researches on effects of gene, environment and gene-environment interaction on developmental dyslexia to provide references for future researches on developmental dyslexia.