内蒙古地区女性人乳头瘤病毒携带情况及TCT检测情况分析

李冰; 陈宇飞

doi:10.11847/zgggws1123838

内蒙古地区女性人乳头瘤病毒携带情况及TCT检测情况分析

李冰,
陈宇飞

Prevalence of human papillomavirus infection (HPV) and TCT results of HPV positive individuals among women in Inner Mongolia Autonomous Region: a hospital-based survey

摘要

摘要:
目的了解2016 — 2018年内蒙古地区女性人乳头瘤病毒（HPV）携带情况。
方法运用核酸检测方法对5 162名女性进行检测，并结合统计学方法对检测结果进行数据分析。
结果 2016年检测总人数为914人，其中HPV阳性为310人，阳性率为33.92 %；2017年检测总人数为1 369人，其中HPV阳性为479人，阳性率为34.99 %；2018年检测总人数为2 879人，其中HPV阳性为799人，阳性率为27.72 %；3年中感染率较高的年龄组为40～49岁。通过对288名HPV携带阳性体检者进行HPV分型检测和液基薄层细胞检测（TCT），结果显示，构成比例居于前3位的HPV基因型分别为HPV16型、HPV45型、HPV18型，所占阳性样本检出比例分别为72.3 %、6.6 %、4.1 %，且复合高危型体检者其TCT检测结果为不典型鳞状细胞（ASCUS）。
结论内蒙古地区女性HPV阳性感染约占三分之一，婚后女性每年应进行HPV核酸检测，同时对阳性携带者建议进行TCT检测。

Abstract:
Objective To examine the prevalence of HPV infection among women in Inner Mongolia Autonomous Region in 2016 − 2018.
Methods We carried out HPV nucleic acid detection among 5 162 women aged 20 years and above taking physical examination at a hospital and then thinprep cytologic test (TCT) was performed among the HPV positive women during a period from 2016 to 2018. Data of the detections were analyzed statistically.
Results The HPV positive rates were 33.92% (310/914), 34.99% (470/1 369), and 27.72% (799/2 879) among the women detected in 2016, 2017, and 2018, respectively. For all the women detected, those aged 40 − 49 years had a higher HPV positive rate. Of the 288 HPV positive women with HPV typing and TCT samples, 72.3%, 6.6% and 4.1% were HPV 16, HPV 45 and HPV 18; 2.4% were lesions of atypical squamous cells undetermined significance or more severe.
Conclusion HPV infection could be detected among about one third of the women in Inner Mongolia Autonomous Region, suggesting that the married women should have annual HPV nucleic acid test.

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