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张瑞仙, 栗旸, 欧秋生, 李建云. 空气污染对女性生育能力及妊娠影响[J]. 中国公共卫生, 2021, 37(6): 1031-1034. DOI: 10.11847/zgggws1125343
引用本文: 张瑞仙, 栗旸, 欧秋生, 李建云. 空气污染对女性生育能力及妊娠影响[J]. 中国公共卫生, 2021, 37(6): 1031-1034. DOI: 10.11847/zgggws1125343
ZHANG Rui-xian, LI Yang, OU Qiu-sheng, . Effects of air pollution on female fertility and pregnancy: a review[J]. Chinese Journal of Public Health, 2021, 37(6): 1031-1034. DOI: 10.11847/zgggws1125343
Citation: ZHANG Rui-xian, LI Yang, OU Qiu-sheng, . Effects of air pollution on female fertility and pregnancy: a review[J]. Chinese Journal of Public Health, 2021, 37(6): 1031-1034. DOI: 10.11847/zgggws1125343

空气污染对女性生育能力及妊娠影响

Effects of air pollution on female fertility and pregnancy: a review

  • 摘要: 空气污染对人类健康带来诸多不利影响,包括对女性生育能力的影响。然而,空气污染损害生育的具体机制并不清楚。本综述对以往有关空气污染对女性生殖的影响进行系统回顾,以全面认识空气污染对人类生育能力的影响。不同人群流行病学及实验室研究中,研究场所和所关注的主要污染物有所不同,流调场所包括石化厂、道路等,污染成分主要包括可吸入颗粒物(PM10)、细颗粒物(PM2.5)、NO2、SO2、O3等煤炭燃烧和交通尾气相关成分。这些研究主要从空气污染物影响卵子发育、受精卵形成与着床、临床受孕、体外受精及胚胎移植、流产、早产等多个不同阶段进行评估总结。各研究尽管存在设计类型不一致、混杂因素多等所带来的偏倚,但在一定程度上为深入研究空气污染对女性生殖影响的机制提供了线索。

     

    Abstract: Air pollution exerts a lot of adverse effects on human health, including on female fertility. However, the exact mechanism of the adverse effects on human fertility is unclear. We conducted a systematic review of previous researches on the influence of air pollution upon female reproduction to fully understand the effect of air pollution on human fertility. The research sites and major pollutants concerned are different among various population epidemiology researches and laboratory studies. The sites of epidemiological investigations included petrochemical plants and traffic roads and the pollutants concerned mainly included particulate matter < 10/2.5 microm in aerodynamic diameter (PM10/2.5), nitrogen dioxide (NO2), sulfur dioxide (SO2), ozone (O3) and other compositions related to coal combustion and traffic exhaust. These studies are mainly based on the evaluation of air pollutants on various stages of egg development, fertilized egg formation and implantation, clinical conception, in vitro fertilization and embryo transfer, abortion, and preterm labor. Despite the bias caused by different design types and many confounding factors, these studies to some extent provide clues for the in-depth study of the mechanism of air pollution's influence on female reproduction.

     

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