Objective  To examine changes in disease burden of cardiovascular diseases (CVD) among residents in Hubei province between 1990 and 2017 and to provide evidences for the precise prevention and control of CVD in the province.

  Methods   The mortality, adjusted mortality rate, years of life loss with premature death (YLLs), adjusted YLLs rate, years lived with disability (YLDs), adjusted YLDs rate, disability adjusted of life years (DALYs) and adjusted DALYs rate were adopted in the study. The estimates of the indicators for CVD among the residents of Hubei province in 2017 were based on the data from Global Burden of Diseases Study 2017 (GBD 2017) and those in 1990 were based on the reports issued in National Yearbook of Health and Family Planning, national information systems of disease surveillance, death registry, and women and children health care and published research literatures.

  Results   Compared to those indicators for disease burden of CVD in 1990, we observed increases in total mortality (by 77.53%), YLLs (40.79%), YLDs (122.17%), adjusted YLDs rate (16.82%), and DALYs (46.69%) but decreases in adjusted mortality rate (23.70%), adjusted YLLs rate (32.84%), and adjusted DALYs (29.62%) among the residents in the province in 2017. The increase in DALY and DALY increasing rate in 2017 among the male residents were 225.28/10 000 person-years and 57.65% and were higher than those among the female residents (171.17/10 000 person-years, 34.38%). The adjusted DALYs rate of CVD (1/100 000) increased with the increment of age, with the values of 1535.02, 16300.29, and 57409.87 in 1990 and 1285.31, 10864.47, and 45105.46 in 2017 for the residents aged 15 – 69, 50 – 69, and ≥ 70 years, respectively. In the terms of adjusted mortality rate, the top five CVDs were cerebral hemorrhage, ischemic heart disease, hypertensive heart disease, ischemic stroke and subarachnoid hemorrhage in 1990 and 2017; while, the rank of the five diseases varied between 1990 and 2017, with the decreased rank from top one to top two for cerebral hemorrhage and from top three to top four for hypertensive heart disease and the increased rank from top two to top one for ischemic heart disease and from top four to top three for ischemic stroke, respectively. In terms of adjusted DALYs rate, the top file CVDs were ischemic heart disease, cerebral hemorrhage, ischemic stroke, hypertension heart disease and subarachnoid hemorrhage in 1990 and 2017; the rank of the five diseases changed slightly between 1990 and 2017, with cerebral hemorrhage descending from top one in 1990 to top two in 2017 and ischemic heart disease ascending from top two to top one.

  Conclusion  Disease burden of cardiovascular diseases increased among residents in Hubei province between 1990 and 2017; the male and aged people are key populations for control and prevention of cardiovascular diseases.