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洪新, 仲来福. 表皮生长因子增高Hela细胞对顺铂敏感性作用的研究[J]. 中国公共卫生, 2000, 16(6): 481-482. DOI: 10.11847/zgggws2000-16-06-01
引用本文: 洪新, 仲来福. 表皮生长因子增高Hela细胞对顺铂敏感性作用的研究[J]. 中国公共卫生, 2000, 16(6): 481-482. DOI: 10.11847/zgggws2000-16-06-01
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Hong Xing, . Epidermal Growth Factor Enhances the Sensitivity of Hela Cells to Cisplatin[J]. Chinese Journal of Public Health, 2000, 16(6): 481-482. DOI: 10.11847/zgggws2000-16-06-01
Citation: Hong Xing, . Epidermal Growth Factor Enhances the Sensitivity of Hela Cells to Cisplatin[J]. Chinese Journal of Public Health, 2000, 16(6): 481-482. DOI: 10.11847/zgggws2000-16-06-01
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表皮生长因子增高Hela细胞对顺铂敏感性作用的研究

Epidermal Growth Factor Enhances the Sensitivity of Hela Cells to Cisplatin

    摘要
  • 摘要: 0.1、1、10μg/L表皮生长因子(EGF)24h预处理及同时处理均增高Hela细胞对顺铂敏感性尤以EGF预处理更明显;10μg/LEGF24h预处理可增高Hela细胞对铂(Pt)的摄入速率.提示Pt摄入速率增高可能是细胞对顺铂敏感性增高的原因.

     

    Abstract: Sensitivity of Hela cells to cisplatin was enhanced by 24h previously or simutaneously treated with 0.1、1、10μg/L EG F,especially treated previously.The rate of Pt uptake was increased by 10μg/L EGF pre-treated.The results sugg est that enhanced Pt uptake may contribute to enhanced sensitivity to cisplat in.

     

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