Abstract: Objective To investigate the apo-B gene polymorphism characters of cerebral infarction in Tianjin area.Methods PCR was used to compare apo-B gene expression in patients with cerebral infarction and control by case-control study.Results The major gene expression among the case and control groups were E⁺、X^-,the relative frequency of E^-、X⁺ in case was outstanding higher than the control.The level of apo-A in patients with E⁺ gene expression was significantly higher than that with E^- gene expression.The level of apo-A in patients with X⁺ gene expression was significantly lower than that with X^- gene expression.The level of apo-B in patients with X⁺ gene expression was significantly higher than that with X^- gene expression.Conclusion The usual gene expression in Tianjin area were E⁺、X^-,E^-、X⁺ gene expression were the risk gene expression of cerebral infarction.