Abstract: Objective To identify the risk factors of toxoplasma gondii infection in maternal women and newborn infants.Methods An epidemiological study on the risk factors of toxoplasma gondii infection was conducted during 1996-1997 in two hospitals of Ningbo.This was carried out by random cluster sampling techniques of target population and clinical survey(including ELISA).During this study a total of 284 maternal women and their newborn infants(also 284) were selected and examined.Results The overall prevalence rates of toxoplasmosis among maternal women and their newborn infants were 5.28%(15/284) and 1.76%(15/284),respectively.Meanwhile,there was marked significant difference in the history of closely contact with animals in maternal women and toxoplasma gondii infection of their newborn infants(OR=28.39,OR 95% CI 3.58～102.32,P<0.01).In addition,other risk factors of toxoplasma gondii infection in maternal women and their newborn infants were analyzed and discussed.Conclusion Based on the study findings,sero-epidemiologic survey in pregnant women showed an important significance in better child-bearing.