Abstract: Objective To study the influence of honey on lipid peroxidation in mice.Methods The 48 Kunming mice was randomly divided into four groups by weight and gender:A(control group),B(pero xidized oil group),C(white honey group,D(dark honey group).Group A was fed by water 0.3ml/d;group B was fed by the mixture(water:perox idized oil=1:1)0.3ml/d;group C was fed by the mixture(acacia-white honey:perox idized oil=1:1)0.30ml/d;group D was fed by the mixture(jujube flow er-dark honey:perox idized oil=1:1)0.30ml/d.Results The MDA level and lipofuscin level of honey group were lower than perox idized oil group(P<0.05),while SOD activity were higher than peroix dized oil group(P<0.05);there was no difference of SOD activity and MDA level between two honey groups;lipofuscin in liver in white honey group was higher than dark honey group(P<0.05).Conclusion Honey can increase the serum SOD activity of mice,and decrease the concentration of serum MDA and lipofuscin in liver.