Abstract: Objective To evaluate viscose rayon workers for cardiovascular manifestations resulting from exposure to carbon disulfide at the level of the threshold limit value of 10mg/m³ long-term.Methods In a cross-sectional study we investigated 367 workers occupationally exposed to CS₂ and a control group(n=125).Results there was a singificant increase in the serum levels of total cholesterol and ApoB(P<0.05).These differences could also be confirmed statisically after multiple stepwise regression analysis.No differences were noted as to concentration of Hdl-ch、Ldl-ch、ApoA-I and so on among three groups.Conclusion The findings may indicate that exposure to CS₂ can increase the levels of total cholesterol and ApoB in the serum,namely,low-level exposure to CS₂ long-term could increase the risk of workes developing CS₂-indued cardiovascular abnormalities.