微量元素与甲型病毒性肝炎关系的研究(2)

Research on Relationship Between Trace Elements and Viral Hepatitis(1)

摘要: 目的探讨微量元素与甲型病毒性肝炎的关系。方法采用1:1配对病例对照,用原子吸收法对HAV感染者血清中的微量元素铜铁锌硒进行测定,并做相应的统计分析。结果HAV患者血清微量元素Zn、Se含量降低,微量元素Fe含量升高。Logistic回归分析表明,Zn是HAV-IgG阳性者向HAV患者转化的重要影响因素,Fe/Zn比值是HAV患者的重要影响因素。结论血清微量元素与HAV存在密切关系:Fe、Zn、Se微量元素是HAV的重要影响因素,在甲型病毒性肝炎的预防诊断及治疗中具有重要作用。

Abstract: ObjectiveTo explore the relationship between trace element and viral hepatitis A.MethodsApairedmatched case-control study was carried out,the trace elements contents of Cu、Fe、Zn、Se in sera was determined by HAV and a control group.Dutum was analyed by T-tets、ANOV、Logistic regression analysis.ResultsSerum contents of Zn and Se in patients with HAV decreased,Fe increased.Lo gistic regression analysis demonstrated that trace elements Zn was important influential factor of transformation form positive HAV-IgG to HAV patients.ConclusionThe viral hepatis Awas related with changes in plasma levels of trace elements.Trace elements Fe、Zn、Se played sig nificant role in prevention and diagnosis and curing for viral hepatis A.