Abstract: ObjectiveTo study the mechanisms of zinc affecting on bone metabolism by analysis of the effects of zinc on bone density and calcium absorption.MethodsTo use the techniques of ⁴⁵⁺Ca tracer and X-roentgenog raphy to examinate mouce fetal limb buds culture in vitro.ResultsCompared with contrast group,zinc-deficient group and zinc-excessive group express decreased bone density and calcium absorption;on the orther hand,zinc-complement supplied group Ⅰ and Ⅱ express increased bone desisty and calcium assorption.ConclusionComplementing zinc properly has potential function of promoting bone for mation,whereas zinc-deficience and zinc-excess retard bone growth and metalization.