Abstract: ObjectiveTo study the asso ciation between some trace elements and viral hepatitis C.MethodsThe contents of tract elements Cu、Fe、Zn and Se in HCV infected cases were detected respectively by spectro phtometer and then the data were analysed statistically by spss for win 9.0.ResultsCompared with the control group,contents of Zn in serum was lower(P<0.001),while Cu,Cu/Zn and Fe/Zn were higher(P<0.01)in anti-HCV positive group,the concents of Zn and Se were lower(P<0.001),Cu/Zn and Fe/Zn were also higher(P<0.001)in HCV patients group.Logistic regression analysis showed that trace elements Cu and Zn of anti-HCV positive group and Se of HCV patients group should be involved in the regression equation.ConclusionThere was a close association between tract elements Zn、Se、Cu、Fe and HCV.Cu and Zn affected anti-HCV positive people apparently,while Se had remarkable effect on HCV patients.