住院患者T细胞白血病病毒Ⅰ/Ⅱ血清流行病学调查

Epidemiological Investigation on HTLV-Ⅰ/Ⅱ among Hospitalized Patients in Liaoning Area

摘要: 目的了解辽宁地区住院患者人类T细胞白血病病毒Ⅰ/Ⅱ(HTLV-Ⅰ/Ⅱ)的流行情况.方法采用酶联免疫吸附法和蛋白印迹方法检测患者血清中的HTLV-Ⅰ/Ⅱ抗体.结果在4103份住院患者的血清标本中,仅有1例为HTLV-Ⅰ阳性,总阳性率为0.024%,其中黑龙江和辽宁省内患者的HTLV-Ⅰ/Ⅱ感染率分别为4%(1/25)和0%(0/3865).17例人类免疫缺陷病毒感染者的血清HTLV-Ⅰ/Ⅱ抗体检测均为阴性.结论辽宁地区的HTLV-Ⅰ/Ⅱ感染率很低.

Abstract: Objective To invest igate the prevalence of HTLV-Ⅰ/Ⅱin Liaoning area.Methods HTLV-Ⅰ/Ⅱantibody were screened and confirmed using enzyme linked immunosorbent assay(ELISA)and Western Blot(WB),respectively.Results Of 4 103 hospitalized patients,only one was confirmed to be infected with HTL V-Ⅰ,with a HTLV-Ⅰ/Ⅱ infection rate 0.024%,of which the infection rate in Heilongjiang province was 4%(1/25),in Liaoning province was 0%(0/3 865).The HTLV-Ⅰ/Ⅱinfection rate of 17 HIV infected persons was negative.Conclusion The HTLV-Ⅰ/Ⅱinfection rate in Liaoning area was low.