沙漠热环境负重行军对淋巴细胞HSP70的影响

刘兵; 邬堂春; 陈胜; 吴志豪; 徐文; 张雪玲

doi:10.11847/zgggws2003-19-04-07

沙漠热环境负重行军对淋巴细胞HSP70的影响

Effects of marching with load of 1.5 kilograms in dry-heat desert on heat shock protein 70 in human lymphocyte

摘要

摘要:
目的探讨沙漠热环境负重行军者血淋巴细胞HSP70的变化规律.
方法对沙漠干热环境中以不同速度和时间负重行军的54名战士和14名对照者血淋巴细胞HSP70进行对比分析.
结果相同行军时间的不同行军速度间淋巴细胞HSP70有显着性差异(P < 0.05);3.5km/h行军3h组淋巴细胞HSP70明显高于对照和行军2h组(P < 0.05): 5.0km/h行军1.2h组血淋巴细胞HSP70明显高于对照和行军3h组(P < 0.05).
结论随行军速度和时间的增加, 淋巴细胞HSP70增高; 当行军速度和时间达到一定水平后, 机体淋巴细胞HSP70明显增加.血淋巴细胞HSP70作为热损伤和热耐受的监测指标较血浆HSP70敏感.

Abstract:
Objective To explore the regulation of heat shock protein 70(HSP70)in human lymphocyte in case of marching without load in dry-heat desert.
Methods The lymphocyte HSP70 of 54 marchers at different speed at different time and 14 controls were detected.
Results There was signficant difference between different speeds at the same time(P < 0.05);The lymphocyte HSP70 of group for 3 hours was obviously more than that of the control and the group for 2 hours at 3.5km/h; The level of HSP70 for 1 and 2 hours is more than the control at 5.0km/h(P < 0.05), but less than for 3 hours(P < 0.05).
Conclusion The lymphocyte HSP70 increased with speed and time.The blood lymphocyte HSP70 was more sensitive than plasma HSP70 in the monitor of heat injure and heat tolerance.

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