2690名献血员血清学检测指标的分析

叶冬青; 郝加虎; 黄芬; 余新炳

doi:10.11847/zgggws2003-19-04-39

2690名献血员血清学检测指标的分析

Study on sero-indexes among 2690 qualified blood donors

摘要

摘要:
目的了解合格献血员其它常见病原体的感染状况; 为提高血液质量提供科学依据.
方法用ELISA法检测HAV-IgM、抗-HBc、HBeAg和抗-HBe; 用EIA法检测抗-EBVIgA、抗-HCMV, 用间接血凝法检测弓形虫.
结果第一阶段研究中, HAV、HBeAg、抗-HBe、抗-HBc、HCMV、EBV, 弓形虫7项中至少有一项阳性者为30.7%, 第二阶段HBeAg、抗-HBe、抗-HBc、HCMV、EBV5项中至少有1项阳性者为43.2%.表明献血员血液中存在着不同程度的HAV、HBV、HCMV、EBV、弓形虫的感染.
结论对于献血员除要检测常规项目外, 有必要检测HBeAg、抗-HBc、抗-HCMV、抗-EBV和弓形虫抗体等血清学指标, 特别是对输给孕妇、免疫功能低下者、婴幼儿、恶性肿瘤、器官移植患者的血液, 以减少输血后疾病的发生.

Abstract:
Objective To understand infectious status of other common pathogens among donors and to provide scientific basis for increasing blood quality.
Methods HAV-IgM, anti-HBc, HBeAg, anti-HBe were tested by enzyme linked immunosorbent assay(ELISA); Anti-EBV-IgA, anti-HCMV and anti-toxoplasm were tested by enzyme immunoassay (EIA)and indirect blood agglutination, respectively.
Results In the first stage of the study, the percentage of donors that had at least a positive index among HAV, HBeAg, anti-HBe, anti-HBc, anti-HCMV, anti-EBV, anti-toxoplasm(7 indexes)was 30.7%.In the second stage of the study, the percentage of donors thathad at least a positive index among HBeAg, anti-HBe, anti-HBc, anti-HCMV, anti-EBV(5 indexes)was 43.2%.
Conclusion Besides testing routine indexes, it was necessary that HBeAg, anti-HBc, anti-HCMV, anti-EBV and anti-toxoplasm be tested among donors, which can lower the incidene of transfusion transmitted diseases.

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