大豆多肽对辐射的保护功能

Study on radioprotective effect of bacillus subtilis

摘要:
目的研究大豆多肽的辐射保护功能。
方法以每日0.21, 0.42, 126g/(kg·bw)大豆多肽胶囊灌喂小鼠60d, 在第30d给予一次性全身γ射线照射, 观察小鼠辐照后30d存活率、平均存活时间、白细胞总数、骨髓细胞DNA含量及血清溶血素水平。
结果大豆多肽能使辐照后小鼠30d存活率明显增高、平均存活时间延长、白细胞总数明显增加, 能提高骨髓细胞DNA含量和血清溶血素水平。
结论大豆多肽具有辐射保护作用。

Abstract:
Objective To research the radioprotective effect of bacillus subtilison ⁶⁰Co-γ-ray-induced injury.
Methods Mice were treated with three different dosesof bacillus subtilis in 60 days. All groups were irradiated once with ⁶⁰Co γ-ray on thirtieth-day, and then the difference in survival rate, average survival time, the changes in white blood cells, quantity of DNA in marrow cell and serum hemolysin were observed.
Results The 30-day survival rate, average survival time, the WBC counts, quantity of DNA in marrow cell and serum hemolysin of Bacillus subtilis-protected mice were all much higher than those of the control group.
Conclusion Bacillus subtilis had significant anti-radiation effect.