妊娠早期被动吸烟与不良妊娠结局的队列研究
Longitudinal study on adverse pregnancy outcomes and passive smoking during first trimester pregnancy of city women
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摘要:目的 分析城市孕早期妇女被动吸烟状况, 探讨被动吸烟对不良妊娠结局的影响, 减少不良妊娠结局的发生。方法 调查孕早期妇女被动吸烟状况, 将其分成被动吸烟组与无被动吸烟组, 追踪其妊娠结局, 采用χ2检验和Logistic回归分析方法, 分析被动吸烟与不良妊娠结局的关系。结果 城市孕早期妇女被动吸烟率为38.2%, 被动吸烟与不良妊娠结局呈一定的剂量-反应关系, 每日被动吸烟的时间越长发生不良妊娠结局的可能性就越大, 每日被动吸烟的时间超过3h对不良妊娠有显著影响。结论 被动吸烟可使不良妊娠发生的危险增加, 每日被动吸烟的时间超过3h是不良妊娠的强危险因素。加强孕前对孕妇的宣教和指导, 尽量避免暴露于吸烟环境, 可减少不良妊娠结局的发生。Abstract:Objective To investigate the distribution of passive smoking in first trimester pregnant women of city, and to study the relationship betw een passive smoking and adverse pregnancy outcomes.Methods Maternal passive smoking status was determined by questionnaire, then two cohorts of passive smoking and non passive soking were gotten.Pregnancy out comes were followed up.Chi Square test and Logistic regression analysis were used.Results The per centage of passive smoking in first trimester pregnant women was 38.2%.The time exposed to passive smoking per day was related with adverse pregnancy outcome.Exposed to passive smoking more than 3 hours per day could highly increase risk of adverse pregnancy outcomes.Conclusion Adverse pregnancy outcomes were associated with passive smoking, especially exposed to passive smoking more than 3 hours per day.Women should be advised to avoid environmental tobacco smoke exposure.
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