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姜楠. HIV携带10年者T淋巴细胞亚群检测分析[J]. 中国公共卫生, 2005, 21(8): 942-943. DOI: 10.11847/zgggws2005-21-08-24
引用本文: 姜楠. HIV携带10年者T淋巴细胞亚群检测分析[J]. 中国公共卫生, 2005, 21(8): 942-943. DOI: 10.11847/zgggws2005-21-08-24
JIANG Nan. Survey and analysis on T lymph cell sub-group of individuals infected by HIV for 10 years[J]. Chinese Journal of Public Health, 2005, 21(8): 942-943. DOI: 10.11847/zgggws2005-21-08-24
Citation: JIANG Nan. Survey and analysis on T lymph cell sub-group of individuals infected by HIV for 10 years[J]. Chinese Journal of Public Health, 2005, 21(8): 942-943. DOI: 10.11847/zgggws2005-21-08-24

HIV携带10年者T淋巴细胞亚群检测分析

Survey and analysis on T lymph cell sub-group of individuals infected by HIV for 10 years

  • 摘要:
      目的   了解HIV携带10年者T淋巴细胞亚群现状, 制订救治方案, 指导高效抗逆转录病毒治疗。
      方法   采用美国FACSCount流行细胞仪, 检测HIV感染者外周血中CD 4、CD 8T细胞绝对值数。
      结果   检测HIV感染者836例, CD 4淋巴细胞 < 200/mm 3者180例, 占21.53%;CD 4T淋巴细胞 > 200/mm 3者656例, 占78.7%。CD 4/CD 8 < 1者779例, CD 4/CD 8 > 1者57例。
      结论   长期存活的HIV感染者CD 4T淋巴细胞计数10年内保持在正常范围之内; 部分感染者已进入AIDS期。在无症状的HIV感染者中存在免疫力极度低下者, 由高水平的T淋巴细胞的抗病毒作用而使其处于无症状期。

     

    Abstract:
      Objective   To get a general idea about the existing T-lymph cells sub group o f the individuals infected by HIV for 10 years, and to work out a therapy, and to guide the highly active antiretroviral therapy.
      Methods   Absolute value of CD 4, CD 8 T-lymph cells in the peripheral blood of the infected individuals were detected with American FACSCount flow cytometer.
      Results   836 infected individuals were detected, 180 indivduals: CD 4 T-lymph cells < 200/mm 3(21.53);656 individuals, CD 4 T-lymph cells > 200/mm 3(78.7%), 779 indiriduals: CD 4/CD 8 < 1;57 individuals: CD 4/CD 8 > 1.
      Conclusion   CD 4, CD 8 T-lymph cells of individuals infected by HIV who survived for a long time remained normal within 10 years, but some of them dev eloped into AIDS.Owing to the high-level of CD 8 T-lymphocyte, the HIV patients whose immunity was extremely low, still had not anysymptom.

     

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